The Bridge

Providing an educational resource for individuals to learn more about hereditary ATTR (hATTR) amyloidosis

hATTR amyloidosis is an autosomal dominant disorder caused by mutations in the transthyretin (TTR) gene. In the disease continuum of hATTR amyloidosis, some individuals present primarily with polyneuropathy symptoms, historically known as familial amyloidotic polyneuropathy (FAP), and other individuals present primarily with cardiomyopathy symptoms, historically known as familial amyloidotic cardiomyopathy (FAC).

Learn more about hATTR amyloidosis

Ron Jr. and Don, living with hATTR amyloidosis

The time for education is now

The Bridge program is about providing education, spreading awareness, and facilitating conversation about hATTR amyloidosis among affected individuals and their families.

The Bridge provides individuals with an array of educational resources designed to help them and their family. The Bridge is also a valuable resource for undiagnosed individuals who may be experiencing symptoms or know of a family member who is diagnosed and wants to learn more about hATTR amyloidosis.

Alnylam Act

Alnylam is sponsoring no-charge third-party genetic testing and counseling for individuals who may carry a gene mutation known to be associated with hereditary ATTR (hATTR) amyloidosis. The Alnylam Act™ program was created to reduce barriers to genetic testing and counseling to help people and their healthcare providers make more informed decisions about their health.

The genetic testing service is available in the United States and Canada and the genetic counseling service is available in the United States.

Genetic testing and counseling may help to:

  • Identify risk of disease for patients and their family members
  • Shorten the time to diagnosis and prevent misdiagnoses
  • Determine if patients are eligible to participate in clinical trials
  • Provide information about support resources such as patient advocacy organizations

These services are available only in the United States. At no time does Alnylam receive patient identifiable information.

Resources for Healthcare Professionals

Neuropathic Red-flag Symptoms Flashcard
A guide to the key symptoms of hATTR amyloidosis for neurologists

Cardiac Red-flag Symptoms Flashcard
A guide to the key symptoms of hATTR amyloidosis for cardiologists

Resources for Patients

Family Discussion Guide
Tips for starting the conversation with your family and a list of resources for further education

A Closer Look at hATTR Amyloidosis
An overview of how the condition occurs, its hereditary nature, and the symptoms that individuals may experience

Family Health Tree
A tool to help patients map their family’s history of hATTR amyloidosis, including symptom tracking, diagnosis time, and more

Healthcare Professional Discussion Guide
Information and tips for talking to your healthcare professional about hATTR amyloidosis

Healthcare Professional Fact Sheet
An informational flashcard that individuals can provide to their healthcare professional to help educate about hATTR amyloidosis

Family History Book
A powerful story about one family's battle with hATTR amyloidosis over the course of four generations and their determination to move foward

Sign up to receive updates.

References:

Hawkins PN, Ann Med. 2015;47(8):625-638.
Ando Y, Orphanet J Rare Dis. 2013;8:31.
Rapezzi C, Eur Heart J. 2013;34(7):520-528.
Adams D, The XVth International Symposium on Amyloidosis. Uppsala, Sweden: ISA International Society of Amyloidosis; July 3-7, 2016. PA 82.

Sign up to receive updates about hereditary ATTR amyloidosis from Alnylam Sign Up