The Bridge

Providing an educational resource for individuals to learn more about hereditary ATTR (hATTR) amyloidosis

hATTR amyloidosis is an autosomal dominant disorder caused by mutations in the transthyretin (TTR) gene. In the disease continuum of hATTR amyloidosis, some individuals present primarily with polyneuropathy symptoms, historically known as familial amyloidotic polyneuropathy (FAP), and other individuals present primarily with cardiomyopathy symptoms, historically known as familial amyloidotic cardiomyopathy (FAC).

Learn more about hATTR amyloidosis

Ron Jr. and Don, living with hATTR amyloidosis

The time for education is now

The Bridge program is about providing education, spreading awareness, and facilitating conversation about hATTR amyloidosis among affected individuals and their families.

The Bridge provides individuals with an array of educational resources designed to help them and their family. The Bridge is also a valuable resource for undiagnosed individuals who may be experiencing symptoms or know of a family member who is diagnosed and wants to learn more about hATTR amyloidosis.

Alnylam Act

Alnylam Pharmaceuticals is sponsoring third-party genetic testing and counseling programs for individuals who may carry a gene mutation known to be associated with hereditary ATTR amyloidosis at no charge.

The Alnylam Act™ program (formerly known as Alnylam Assist™)
  • Potentially enables diagnosis through genetic screening
  • Provides genetic counseling to help people make more informed decisions about their health
  • Offers genetic counseling before, during, and after genetic screening

These services are available only in the United States. At no time does Alnylam receive patient identifiable information.

Resources for Healthcare Professionals

Neuropathic Red-flag Symptoms Flashcard
A guide to the key symptoms of hATTR amyloidosis for neurologists

Cardiac Red-flag Symptoms Flashcard
A guide to the key symptoms of hATTR amyloidosis for cardiologists

Resources for Patients

Family Discussion Guide
Tips for starting the conversation with your family and a list of resources for further education

A Closer Look at hATTR Amyloidosis
An overview of how the condition occurs, its hereditary nature, and the symptoms that individuals may experience

Family Health Tree
A tool to help patients map their family’s history of hATTR amyloidosis, including symptom tracking, diagnosis time, and more

Healthcare Professional Discussion Guide
Information and tips for talking to your healthcare professional about hATTR amyloidosis

Healthcare Professional Fact Sheet
An informational flashcard that individuals can provide to their healthcare professional to help educate about hATTR amyloidosis


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Rapezzi C, Eur Heart J. 2013;34(7):520-528.
Adams D, The XVth International Symposium on Amyloidosis. Uppsala, Sweden: ISA International Society of Amyloidosis; July 3-7, 2016. PA 82.

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